Play a card from your hand; place a chip on a corresponding space on the game board. When you have five in a row, it's a Sequence. Learn to block your opponents and remove their chips. Watch out for the jacks - they're wild. Two-eyed jacks are wild, while one-eyed Jacks allow an opponent's checker to be removed.
The game ends when someone has reached a specified number of connections. With a little strategy and a little luck, you're a winner!