Munchkin Pathfinder, which includes 168 cards and uses the setting of the Pathfinder role-playing game from Paizo Publishing, can be played as a standalone game or combined with any other core Munchkin game. That said, while Munchkin Pathfinder includes Classes and something new for this set – Factions – the game does not use Races.
As for what you'll find in the set, you can try out new classes like Alchemist and Witch; join a faction to become an Eagle Knight or a Red Mantis Assassin; or arm yourself with the T-Bone Stake and the Armor of Insults. You'll need those latter items to defeat the Ghoul Friday, the Whispering Tyrant, and especially Lamashtu, the Mother of Monsters. But first you'll have to fight your way through all those goblins...and kill them and take their stuff!
Munchkin Pathfinder Deluxe contains the same cards, die and rules as Munchkin Pathfinder, but also includes a game board, pawns and plastic stands. Munchkin Pathfinder Deluxe also features a brand-new mechanism — "Factions" — and a new D6 for the iconic Pathfinder Goblin.